Eight-time champion Serena Williams has pulled back from the Miami Open as a result of knee damage.
American Williams achieved the third round on Friday by beating Sweden’s Rebecca Peterson, just the seventh match she has finished in 2019.
The 23-time Grand Slam champ was set to confront Wang Qiang in the last 32 yet the Chinese 27-year-old currently gets a bye.
World number one Naomi Osaka endured a stun three-set misfortune to Hsieh Su-wei, positioned 27th, in their third-round tie.
Williams, who said she was “frustrated”, has now pulled back from two successive WTA occasions, following her retirement from a week ago’s competition in Indian Wells as a result of a viral sickness.
The 37-year-old last asserted the Miami title in 2015, with her last Grand Slam win coming at the 2017 Australian Open, a triumph which moved her one behind Margaret Court’s record of 24 noteworthy singles titles.
“I plan to be back one year from now to play at this exceptional competition before the extraordinary fans here in Miami,” she said.
Japan’s Osaka, 21, has won the previous two Grand Slam competitions – the 2018 US Open and the Australian Open in January – however went down 4-6 7-6 (9-7) 6-3 to Hsieh on Saturday.
“This was an enthusiastic success for me,” said the 33-year-old Taiwanese, who will currently confront either Caroline Wozniacki of Denmark or Romanian Monica Niculescu in the fourth round.
“Whenever you beat one of the best players it is stunning.”
World number two Petra Kvitova was tried by Croat Donna Vekic however won 6-4 3 6-4 to reach cycle four.
The Czech two-time Wimbledon champion and third seed needed to battle for over two hours against Vekic.
She will currently meet France’s Caroline Garcia in the fourth round. Garcia beat German fifteenth seed Julia Gorges 6-0 7-5.
Indian Wells champion Bianca Andreescu beat eighth seed and world number four Angelique Kerber of Germany for the second time in seven days.
The Canadian, who beat Kerber to win her lady WTA title last Sunday, won 6 4 6-1 and stretched out her series of wins to 10 matches.